Short answer is no, you cannot have one row/column that is both editable and formula driven.
The only time you can do that is by using versions and restricting the scope of formula from within the blueprint. This restricts the formula to certain versions and other versions are editable but again, this isn't one row/column
If you are using Versions in your model, you can leverage the Formula Scope functionality to have a formula apply to a specific version, and then leave the formula blank for another version. You would typically use this approach if you are doing something like importing actuals, but using a formula to generate a forecast.
Essentially if you are using a formula for line item , you would not be able to manually input values , however if your module uses native versions , there is a possibility that the formula can be restricted to be applied to only particular versions (Actual , or current ) etc. Meaning that for the other versions where scope is not applicable , values can be entered manually